Jimmy Kimmel rounded up an all-star cast for his latest “Mean Tweets” segment, during which celebrities read mean tweets that have been posted about them.

The Movie Edition of the popular segment featured big stars like Christoph Waltz, Patricia Arquette, George Clooney, Jessica Chastain, Eddie Redmayne, Susan Sarandon, Kevin Costner, Emily Blunt, Zach Galifianakis, Kevin Hart, Richard Dreyfuss, Cate Blanchett, Seth Rogen, Oscar Isaac, Taraji P. Henson and Sean Penn.

Of course, they all had a good sense of humor about it or they likely wouldn’t participate in the segment.

Sean Penn managed to keep a straight face when he read, "Sean Penn: 1) has a penis nose, 2) has a scrotum face, 3) has an anus mouth, 4) is a butthole, while Clooney had a good laugh at, "If that gross ratty old man George Clooney can find a girl... you regular fellas out there in the twitterverse must be drowning in p---y."

Meanwhile, some responded to the tweet, like Susan Sarandon. "Tired of susan sarandon having her big fat saggy boobs in my face," she read from her mean tweet card, responding, "Oh, you wish!”